quinta-feira, 6 de outubro de 2011

Música sobre catálise enzimática

Esta música é sobre a catálise enzimática, e é uma adaptação feita pelo Dr. Ahern (www.davincipress.com/metabmelodies.html) da canção Close to You.


My enzymes
Truly are inclined
To convert
Things they bind
Turn the key

How do cells
Regulate these roles?
Allo-ster-ic controls
Two forms, see
States R and T

Competing inhibition keeps
The substrates from the active site
They raise Km, but leave Vmax and shirk
While the non-competers bind elsewhere
And lift the plot made on Lineweaver-Burk

Other ways
Enzymes can be blocked
When things bind
Then get locked
Stuck not free
Tied to the key

Penicillin’s action stops
Peptidoglycan cross-links in
Bacterial cell walls in awesome ways
Beta lactam ring’s reactive site
Starts bonding with D-D-transpeptidase

So there are
Several enzyme states
Counteract-ing substrates
Now you see
Blocking the key

Have to be controlled
Some get slowed
Put on hold
It's sublime
How the enzymes
(slow) Cat-a-lyze

ahhhhhhhhhhhhhhhhhhh - cat-a-lyzeahhhhhhhhhhhhhhhhhhh - cata-
lyzeahhhhhhhhhhhhhhhhhhh - cat-a-lyze

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