Mapa metabólico sobre a utilização de propionil-CoA

Vídeo sobre a oxidação de ácidos gordos

Música sobre a oxidação dos ácidos gordos

O Dr. Ahern adaptou a canção When Johnny Comes Marching Home , tornando-a uma canção sobre a oxidação dos ácidos gordos.

Faça download da música aqui

When Acids Get Oxidized

The fatty acids carried by
CoA, CoA
Are oxidized inside the
mi-to-chon-dri-ay
They get to there as you have seen
By hitching rides on carnitine
Then it goes away
When acids get oxidized

Electrons move through membranes, yes
It’s true, it’s true
They jump from complex I onto
Co-Q, Co-Q
The action can be quite intense
When building proton gradients
And its good for you
When acids get oxidized

The protons pass through complex V
You see, you see
They do this to make lots of
A-TP, TP
The mechanism you should know
Goes through the stages L-T-O
So there's energy
When acids get oxidized
.

Música sobre a síntese de ácidos gordos

Quem diria que a música When Johnny Comes Marching Home poderia dar origem a uma música sobre a síntese de ácidos gordos? O Dr. Ahern, claro! :)

Faça download da música aqui

When Acids Are Synthesized

The 16 carbon fatty acid, palmitate
Gets all the carbons that it needs from acetate
Which citric acid helps release
From mitochondri - matrices
Oh a shuttle's great
When acids are synthesized

Carboxylase takes substrate and it puts within
Dioxy carbon carried on a biotin
CoA's all gain a quick release
Replaced by larger ACPs
And it all begins
When acids are synthesized

A malonate contributes to the growing chain
Two carbons seven times around again, again
For saturated acyl-ates
There's lots of N-A-DPH
That you must obtain
When acids are synthesized

Palmitic acid made this way all gets released
Desaturases act to make omega-threes
The finished products big and small
Form esters with a glycerol
So you get obese
When acids are synthesized
.

Música sobre os ácidos gordos

Esta música do Dr. Ahern (www.davincipress.com/metabmelodies.html) é sobre o papel dos ácidos gordos nas nossas células e tem por base a canção Halls of Montezuma.

http://www.mediafire.com/?2exx92e6264493c

Fatty Acids in Our Cells

From the fatty acids in our cells

To the lipids in our brains

We are made of biochemicals

Built in metabolic chains

Using glycolytic ATP

And electron energy

We can synthesize most everything

With the help of Delta G

A cell will tend to pump out sodium

But potassium it imports

It accomplishes this magic with

ATPase antiports

Our bilayer lipid membranes

Protect the cells' insides

Partly made of sphingolipids

We know as gangliosides

When it comes to regulation

The little cell has got it made

It phosphorylates a lot of things

With its own kinase cascade

Stimulated at a hormone site

Metabolic yang and yin

That's turned on by epinephrine

And turned off by insulin